Extracting Tractosemas from a displacement probability field for tractography in DW-MRI

by Barmpoutis, A. | Vemuri, B. C. | Howland, D. | Forder, J. R.

In Proceedings of MICCAI08: Int. Conf. on Medical Image Computing and Computer Assisted Intervention, LNCS, vol. 5241, September 6-10, 2008, pp. 9-16. https://doi.org/10.1007/978-3-540-85988-8_2

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Description

In this paper we present a novel method for estimating a field of asymmetric spherical functions, dubbed tractosemas, given the intra-voxel displacement probability information. The peaks of tractosemas correspond to directions of distinct fibers, which can have either symmetric or asymmetric local fiber structure. This is in contrast to the existing methods that estimate fiber orientation distributions which are naturally symmetric and therefore cannot model asymmetries such as splaying fibers. We propose a method for extracting tractosemas from a given field of displacement probability iso-surfaces via a diffusion process. The diffusion is performed by minimizing a kernel convolution integral, which leads to an update formula expressed in the convenient form of a discrete kernel convolution. The kernel expresses the probability of diffusion between two neighboring spherical functions and we model it by the product of Gaussian and von-Mises distributions. The robustness of our model in estimating accurate fiber orientations is validated via experiments on synthetic and real diffusion-weighted magnetic resonance (DW-MRI) datasets from an isolated rat hippocampus and a cats spinal cord.

Additional information

Author

Barmpoutis, A., Vemuri, B. C., Howland, D., Forder, J. R.
Journal

In Proceedings of MICCAI08: Int. Conf. on Medical Image Computing and Computer Assisted Intervention, LNCS
Volume

5241
Publisher

Springer
Year

2008
Month

September 6-10
Pages

9-16
DOI

https://doi.org/10.1007/978-3-540-85988-8_2

Citation

Citation

Barmpoutis, A., Vemuri, B., Howland, D. and Forder, J., 2008. Extracting Tractosemas from a displacement probability field for tractography in DW-MRI. In Proceedings of MICCAI08: Int. Conf. on Medical Image Computing and Computer Assisted Intervention, LNCS, vol. 5241, pp. 9-16. https://doi.org/10.1007/978-3-540-85988-8_2

BibTex

@article{digitalWorlds:165,
doi = {https://doi.org/10.1007/978-3-540-85988-8_2},
author = {Barmpoutis, A.  and  Vemuri, B. C.  and  Howland, D.  and  Forder, J. R.},
title = {Extracting Tractosemas from a displacement probability field for tractography in DW-MRI},
journal = {In Proceedings of MICCAI08: Int. Conf. on Medical Image Computing and Computer Assisted Intervention, LNCS},
month = {September 6-10},
volume = {5241},
year = {2008},
pages = {9-16}
}

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